Asia Stem Cell Center

Neural Progenitor Cell

Neural Progenitor Cell

Neural Progenitor or Stem Cells (NPCs) can be derived from Adipose or Bone Marrow Mesenchymal Stem Cells (MSC). These cells differentiate into cells of neuronal and glial lineage. Their therapeutic translation has been significantly boosted by the demonstration that MSC display significant also anti-proliferative, anti-inflammatory and anti-apoptotic features in brain. These properties have been exploited in the effective treatment of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis where the inhibition of the autoimmune response resulted in a significant neuroprotection. A significant rescue of neural cells has been achieved also when MSC were administered in experimental brain ischemia and in animals undergoing brain or spinal cord injury.