Asia Stem Cell Center

Rejuvination

rejuvination

Stem Cell for Rejuvination

Characterized by dysfunction of tissues, organs, organ systems and the whole organism, aging results from the reduced function of effective stem cell populations. Organismic rejuvenation is potentially achieved by either removing deleterious substances from old plasma and stem cell niches, or by providing factors that promote young phenotypes in old plasma; indeed, both might be beneficial. If aging is a programmed process coordinated by plasma-borne factors, then exposing cells to the plasma of a particular age should make those cells exhibit a corresponding age phenotype in terms of gene expression profiles.It is considered that organismic rejuvenation could be achieved by exchange of as much blood or plasma as possible to reduce the effects of original blood or plasma. This suggests plasma replacement could be a treatment option for age-related diseases. Recent advances in aging research have demonstrated that old tissue stem cells can be rejuvenated for the purpose of maintaining the old-organ function by youthful re-calibration of the environment where stem cells reside.