Recent progress in diabetes mellitus therapy has focused attention on generation of surrogate \u03b2-cells from mesenchymal stem cells (MSCs) derived adult tissues. In this study, we conducted a phase I clinical trial in patients with type 2 diabetes mellitus in various age between 30- 79 years old who were treated with autologous adipose-derived MSCs transplantation. <\/p>\n\n\n\n
MSCs injected into diabetic patients through catheterization then we measured levels of fasting blood glucose, 2h postprandial blood glucose, insulin, c-peptide pre and post stem cell transplantation, also HbA1c. Levels of blood glucose (fasting and 2h post prandial) and insulin were absolutely decreasing after injection. Meanwhile, level of c-peptide was increasing after injection. Level of HbA1c was significantly decreasing after 3 months injection. Thus, adipose-derived mesenchymal stem cells for treatment tertiary failure diabetes mellitus type 2 was better than insulin treatment only.<\/p>\n\n\n\n
Author<\/strong> : Purwati, Sony Wibisono, Ari Sutjahjo, Askandar T.J., Fedik A. Rantam<\/p>\n","protected":false},"excerpt":{"rendered":" Recent progress in diabetes mellitus therapy has focused attention on generation of surrogate \u03b2-cells from mesenchymal stem cells (MSCs) derived adult tissues. In this study, we conducted a phase I clinical trial in patients with type 2 diabetes mellitus in various age between 30- 79 years old who were treated with autologous adipose-derived MSCs transplantation. […]<\/p>\n","protected":false},"author":3,"featured_media":3320,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[50],"tags":[52],"class_list":["post-2636","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-stem-cell","tag-diabetes"],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/asiastemcellcenter.com\/wp-content\/uploads\/2025\/11\/27d4aa02-62b2-4896-9d60-b39b695583db.jpg","_links":{"self":[{"href":"https:\/\/asiastemcellcenter.com\/id\/wp-json\/wp\/v2\/posts\/2636","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/asiastemcellcenter.com\/id\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/asiastemcellcenter.com\/id\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/asiastemcellcenter.com\/id\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/asiastemcellcenter.com\/id\/wp-json\/wp\/v2\/comments?post=2636"}],"version-history":[{"count":0,"href":"https:\/\/asiastemcellcenter.com\/id\/wp-json\/wp\/v2\/posts\/2636\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/asiastemcellcenter.com\/id\/wp-json\/wp\/v2\/media\/3320"}],"wp:attachment":[{"href":"https:\/\/asiastemcellcenter.com\/id\/wp-json\/wp\/v2\/media?parent=2636"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/asiastemcellcenter.com\/id\/wp-json\/wp\/v2\/categories?post=2636"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/asiastemcellcenter.com\/id\/wp-json\/wp\/v2\/tags?post=2636"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}